Possible Benefits and Precautions of Creatine Use for the Elderly
The Root of Creatine’s Benefit for the Elderly
- Reduced Methylation Status Characterizes Old Age
- Creatine Supplementation Enhances Cellular Methylation
- Creatine Supplementation May Help Postpone Mental Senescence
- Precautions of Creatine Supplementation for the Elderly
Creatine Supplementation May Improve Cellular Methylation Status
The single largest drain of the body’s SAM reserves is the synthesis of creatine. By inference therefore, circumventing creatine synthesis should positively influence an individual’s methylation status. And, the best way to avoid the synthesis of creatine is to provide the body with enough dietary creatine to meet its daily needs, thereby bypassing creatine synthesis altogether. That is, dietary creatine supplementation alleviates the need to synthesize creatine and hence, boosts an individual’s methylation status. Therefore, creatine supplementation contributes to a more healthful methylation status, which, in turn, lays down the foundation for all other anabolic processes in the body.
Moreover, essential B vitamins, namely folic acid, vitamin B12 and vitamin B 6, help regenerate SAM after its consumption in cellular methylation reactions. Therefore, to maximize your methylation potential, include these B-vitamins in your creatine supplementing routine as well.
Creatine Supplementation Reduces Serum Homocysteine Levels
Imbalances in SAM metabolism produce a potentially dangerous molecule known as homocysteine. Typically, homocysteine is either cleared from the body, or reconverted into SAM, with the assistance of B-vitamins. However, elevations in serum homocysteine (as a result of excessive cellular methylation, or B-vitamin deficiencies) have been implicated in many of the most insidious human disorders inflicting the elderly. Therefore, creatine supplementation, by the mere fact that it relieves some of the demand on our endogenous SAM reserves, should help mitigate serum homocysteine levels. In fact, this exact prediction has been borne out in a recent scientific study.
For optimal methylation status combine creatine and B-vitamin supplementation for an accentuated anabolic status (enhanced cellular methylation) and improved overall health (reduced serum homocysteine levels).
How to correctly combine creatine and essential B-vitamins to take full advantage of these very important aspects of creatine supplementation is only discussed in Creatine: A practical guide.
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Finally, although the body’s endogenous synthesis of creatine may contribute to elevated homocyteine levels in certain individuals, the importance of creatine in maintaining a positive energy balance cannot be understated. In a sense, creatine synthesis is a necessary evil.
Click here for a more detailed discussion of creatine’s other ergogenic (physical performance enhancing) effects.
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