Creatine in Clinical Trials

Clinical Scenarios Where Creatine is Being Tested

1. Muscular Dystrophy

2. Neurodegenerative Disorders

3. Ischemia and hypoxia

Creatine’s Use in Clinical Trials Stems From its Ability to Bolster Cellular Energy Reserves

Creatine is currently being tested in clinical trials for potential therapeutic use during the treatment of several neurological and neuromuscular disorders. Nonetheless, despite the recent boom in creatine research, our current knowledge of just how creatine supplementation benefits tissues other than skeletal muscle is far from complete. One obvious benefit, however, is creatine’s ubiquitous ability to buffer cellular energy levels – a clear advantage for any cell type in possible danger of energy exhaustion. Another source of broad-reaching benefits has to do with creatine’s positive effect over cellular methylation status. These biochemical mechanisms must be understood in order to take full advantage of creatine supplementation for general health and well-being.

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